Caution should be exercised when Iguratimod is taken alongside other medications. Patients who are already receiving other disease-modifying anti-rheumatic drugs (DMARDs) such as Methotrexate, non-steroidal anti-inflammatory drugs (NSAIDs) like Ibuprofen or Diclofenac, or steroids and other immunosuppressive agents, should only use Iguratimod under strict medical supervision.